Built for Australia's pharmacist registration exam
OPRA Exam Preparation for Overseas Pharmacists
Walk into the OPRA exam properly prepared.
2,500+ MCQs, timed mock exams weighted to the official OPRA blueprint, spaced-repetition flashcards, and a calculations lab.
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2,500+
MCQs
55
Crash Course modules
120
MCQs per mock
80+
Calc lab scenarios
What is the OPRA exam?
The OPRA (Overseas Pharmacist Readiness Assessment) exam is the Australian Pharmacy Council's assessment for internationally qualified pharmacists seeking registration to practise in Australia. It's a 120-question, multiple-choice exam covering five domains — Therapeutics and patient care, Biomedical sciences, Pharmacology and toxicology, Pharmacokinetics and pharmacodynamics, and Medicinal chemistry and biopharmaceutics — assessed against a 70% pass mark.
Read the full OPRA exam guide — eligibility, format & timelineTry before you sign up
Practise OPRA questions before exam day
Every question includes a full clinical explanation, option-by-option reasoning, and a memory tip. This is what OPRA questions actually look like — scenario-based, clinically grounded, no trick trivia.
- Worked explanation for every answer choice
- Core concept + memory tip on every question
- Difficulty rating and domain tag
- Option-by-option reasoning so you learn the why
A 72-year-old woman with type 2 diabetes and stage 3 chronic kidney disease (eGFR 38 mL/min/1.73 m²) is currently prescribed metformin 1 g twice daily. Her recent HbA1c is 7.8%. Which of the following is the most appropriate action?
Click any option to answer
Free · No sign-up needed
The Calculations Lab
Calculation questions are consistently the hardest part of OPRA. Each scenario randomises the patient values so you practise the method, not memorise the answer.
- Cockcroft-Gault & renal dose adjustment
- BSA-based chemotherapy dosing
- Opioid equianalgesic conversions
- Vancomycin AUC dosing & TDM
- mmol/mEq electrolyte calculations
- Alligation & concentration problems
Calculate the CrCl for a 68-year-old female weighing 72 kg, serum creatinine 142 µmol/L.
CrCl = (140 − 68) × 72 × 1.04
──────────────────────────
142
= 38.0 mL/min
Each attempt uses randomised values — you practise the method, not the answer.
Everything you need in one place
Free tier includes 50 MCQs + 5 Crash Course modules + the full Calculations Lab + free study guides. Upgrade to Pro for all 2,500+ MCQs, mock exams & flashcards.
Question Bank
2,500+ exam-style MCQs across all five OPRA domains, with worked explanations, option-by-option reasoning, and difficulty ratings.
Mock Exam
Full 120-question, 150-minute timed simulation, blueprint-weighted to match the real OPRA domain mix.
Flashcards
Spaced repetition across all 2,500+ OPRA cards. Daily due-card review, streak tracking, and interval display — progress syncs to your account.
Calculations Lab
Randomised numerics for every OPRA calculation topic — Cockcroft-Gault, BSA, opioid conversions, vancomycin dosing, and more.
Crash Course
55 high-yield OPRA modules with 239 exam-style MCQs — read the concept, take inline check-questions, then prove it with a scored quiz. Covers all 5 domains.
Free Resources
In-depth OPRA study guides — drug classes, calculations, Australian healthcare topics — free to read, no account needed.
Not just a question dump
The smarter way to prep
Most OPRA prep is a static bank of questions. ClinicalStem tracks where you're weak and points you to what actually moves your score.
Spaced repetition
Miss a question and it comes back right before you'd forget it — one review queue shared across questions and flashcards, scheduled by an SM-2-style algorithm.
Confidence calibration
We track where you're confidently wrong — the dangerous gaps you'd otherwise miss — and surface those topics first.
Know when you're ready
A live readiness gauge against the 70% pass mark, broken down by domain, so you can see where you stand before exam day.
Built specifically for the Australian OPRA exam — not a repurposed international question bank.
Aligned to the official blueprint
Weighted to match the real exam
Mock exams and mixed sets are generated according to the OPRA domain weightings — so your preparation mirrors the actual exam distribution, not just random sampling.
Why ClinicalStem
What sets ClinicalStem apart for overseas-trained pharmacists preparing for the Australian exam.
Built for the real OPRA
Mock exams and mixed sets follow the official OPRA domain weightings, so your prep mirrors the actual exam distribution — not a generic question bank.
Written for Australian practice
Questions are written against Australian references — Therapeutic Guidelines, the AMH and the TGA — with the source cited on every answer, so you can check the key yourself.
Worked answers, not just keys
Each question includes option-by-option reasoning, a core concept, a memory tip, and source references — so you learn the pattern, not just the answer.
Frequently asked questions
What is the OPRA exam?
The OPRA (Overseas Pharmacist Readiness Assessment) exam is the Australian Pharmacy Council's assessment for internationally qualified pharmacists seeking registration to practise in Australia. See the full OPRA exam guide for eligibility, format and the registration pathway.
How many questions are in the OPRA exam?
The OPRA exam is a 120-question, multiple-choice paper delivered under timed conditions — the same format ClinicalStem's mock exams replicate.
What is the OPRA pass mark?
70% is the benchmark most candidates prepare against — it's the readiness threshold used throughout ClinicalStem's practice and mock-exam scoring.
What topics does the OPRA exam cover?
Five domains: Therapeutics and patient care (45%), Biomedical sciences (20%), Pharmacology and toxicology (15%), Pharmacokinetics and pharmacodynamics (10%), and Medicinal chemistry and biopharmaceutics (10%) — see the exam composition breakdown below.
How do I prepare for the OPRA exam?
Most candidates combine a large practice question bank, timed full-length mock exams weighted to the real domain split, spaced-repetition review, and dedicated practice on calculation questions — the pattern ClinicalStem is built around.
Is ClinicalStem suitable for overseas-trained pharmacists?
Yes — it's built specifically for the OPRA exam and overseas-trained pharmacists preparing for Australian registration, with questions written against Australian references (Therapeutic Guidelines, the AMH, the TGA) rather than a generic or international question bank.
Simple, transparent pricing
Start free — everything you need to prepare for the OPRA exam, in one place.
Free
$0
- ✓ 50 MCQs (10 per domain)
- ✓ 5 Crash Course modules
- ✓ Calculations Lab — free forever
- ✓ Flashcards (first 50 cards)
- ✓ Free OPRA study guides & articles
- ✓ Progress tracking & analytics
Pro
Most popular$69/mo
or $179/3 mo · $299/6 mo · cancel anytime
- ✓ All 2,500+ MCQs
- ✓ Timed mock exams (120 MCQs)
- ✓ All 55 Crash Course modules (239 MCQs)
- ✓ Full Calculations Lab — every OPRA numeric type
- ✓ Full flashcard deck + spaced repetition
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